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Miklós Sahin-Tóth Selected Research

Peptide Hydrolases (Proteases)

12/2022Novel p.G250A Mutation Associated with Chronic Pancreatitis Highlights Misfolding-Prone Region in Carboxypeptidase A1 (CPA1).
1/2022Risk of chronic pancreatitis in carriers of loss-of-function CTRC variants: A meta-analysis.
12/2021Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.
3/2020Measuring digestive protease activation in the mouse pancreas.
1/2020Inactivation of mesotrypsin by chymotrypsin C prevents trypsin inhibitor degradation.
1/2020Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.
1/2019Natural single-nucleotide deletion in chymotrypsinogen C gene increases severity of secretagogue-induced pancreatitis in C57BL/6 mice.
1/2019Genetics, Cell Biology, and Pathophysiology of Pancreatitis.
1/2019Protease-Sensitive Pancreatic Lipase Variants Are Associated With Early Onset Chronic Pancreatitis.
10/2018Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.
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Miklós Sahin-Tóth Research Topics

Disease

54Chronic Pancreatitis
08/2023 - 11/2003
51Pancreatitis
05/2024 - 06/2002
28Hereditary pancreatitis
03/2023 - 02/2002
4Autolysis
01/2020 - 07/2007
3Edema (Dropsy)
03/2023 - 11/2018
3Cystic Fibrosis (Mucoviscidosis)
01/2022 - 02/2015
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2017 - 05/2003
2Necrosis
03/2021 - 11/2018
2Neoplasms (Cancer)
11/2015 - 02/2015
2Autoimmune Pancreatitis
02/2015 - 09/2010
2Pancreatic Diseases (Pancreatic Disease)
08/2006 - 05/2003
1Chronic Disease (Chronic Diseases)
03/2022
1Alcoholic Pancreatitis
01/2020
1Seizures (Absence Seizure)
01/2020
1Insulin Resistance
01/2019
1Genetic Predisposition to Disease (Genetic Predisposition)
01/2019
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2019
1Gallstones (Gallstone)
01/2019
1Atherosclerosis
01/2019
1Fibrosis (Cirrhosis)
11/2018
1Pain (Aches)
03/2018
1Adenocarcinoma
04/2016
1Abdominal Pain (Pain, Abdominal)
01/2016
1Ovarian Neoplasms (Ovarian Cancer)
11/2015
1Rare Diseases (Rare Disease)
02/2015
1Ganglion Cysts (Ganglion)
11/2006
1Alcoholism (Alcohol Abuse)
05/2003

Drug/Important Bio-Agent (IBA)

48TrypsinogenIBA
09/2023 - 02/2002
29TrypsinIBA
08/2023 - 02/2002
16EnzymesIBA
09/2022 - 01/2008
14chymotrypsin CIBA
08/2023 - 04/2006
14Peptide Hydrolases (Proteases)FDA Link
12/2022 - 01/2008
13Kazal Pancreatic Trypsin InhibitorIBA
05/2024 - 01/2005
10CeruletideIBA
03/2023 - 02/2010
9ChymotrypsinFDA Link
03/2023 - 12/2016
7Carboxypeptidases A (Carboxypeptidase A)IBA
12/2022 - 10/2013
7Protein Isoforms (Isoforms)IBA
03/2022 - 05/2003
7Peptides (Polypeptides)IBA
12/2021 - 11/2003
6Serine Proteases (Serine Protease)IBA
08/2023 - 04/2005
6Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2009
4Cathepsin BIBA
01/2023 - 06/2002
4SecretagoguesIBA
01/2023 - 10/2018
3Trypsin InhibitorsIBA
11/2022 - 07/2005
3AmylasesFDA Link
03/2021 - 11/2018
3NucleotidesIBA
01/2019 - 05/2011
3chymotrypsinogen CIBA
01/2019 - 04/2006
3Amino AcidsFDA Link
12/2016 - 02/2002
2Pancreatic Elastase (Elastase)IBA
09/2022 - 01/2019
2ChloridesIBA
01/2022 - 02/2015
2Bicarbonates (Hydrogen Carbonate)IBA
01/2022 - 09/2015
2Ethanol (Ethyl Alcohol)IBA
01/2020 - 02/2015
2Protease Inhibitors (Protease Inhibitor)IBA
01/2019 - 10/2018
2Enzyme Precursors (Zymogens)IBA
04/2006 - 05/2003
1benzamidineIBA
11/2022
1DabigatranFDA Link
11/2022
1Transcription Factors (Transcription Factor)IBA
01/2022
1Aspartic Acid (Aspartate)FDA Link
12/2021
1polyaspartateIBA
12/2021
1Calcium-Sensing ReceptorsIBA
10/2021
1Carrier Proteins (Binding Protein)IBA
01/2020
1Messenger RNA (mRNA)IBA
01/2020
1Caseins (Casein)FDA Link
01/2020
1Chymases (Chymase)IBA
01/2020
1Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
01/2020
1Peroxidase (Myeloperoxidase)IBA
01/2020
1Lipase (Acid Lipase)FDA Link
01/2019
1Insulin (Novolin)FDA Link
01/2019
1ChymotrypsinogenIBA
10/2018
1erucylphosphocholineIBA
03/2018
1pancreatic lipase related protein 2IBA
01/2018
1trypsinogen activation peptideIBA
12/2017
1DisulfidesIBA
06/2016
1Biomarkers (Surrogate Marker)IBA
04/2016
1Cholecystokinin B ReceptorIBA
04/2016
1Bile Acids and Salts (Bile Acids)IBA
01/2016
1Ion Channels (Ion Channel)IBA
01/2016
1ErbB Receptors (EGF Receptor)IBA
11/2015
1CarboxypeptidasesIBA
10/2015
1AnionsIBA
09/2015
1Fatty Acids (Saturated Fatty Acids)IBA
02/2015
1Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA
02/2015
1RNA Precursors (Precursor, mRNA)IBA
05/2014
1Phenobarbital (Luminal)FDA Link
12/2011
1RNA (Ribonucleic Acid)IBA
09/2010
1AutoantibodiesIBA
09/2010
1Dexamethasone (Maxidex)FDA LinkGeneric
03/2010
1Cathepsin LIBA
02/2010
1Taurocholic Acid (Sodium Taurocholate)IBA
02/2010
1LectinsIBA
05/2009
1Pancreatitis-Associated ProteinsIBA
05/2009
1Protein Sorting Signals (Signal Peptide)IBA
05/2007
1Retinaldehyde (Retinal)IBA
11/2006
1Codon (Codons)IBA
06/2006

Therapy/Procedure

8Therapeutics
05/2024 - 02/2015
2Injections
03/2022 - 01/2020
2Cholecystectomy
01/2019 - 02/2015
2Endoscopic Sphincterotomy
01/2019 - 02/2015
1Conservative Treatment
02/2015
1Critical Care (Surgical Intensive Care)
02/2015
1Fluid Therapy (Oral Rehydration Therapy)
02/2015